UCSD Next-Generation Sequencing and Informatics Symposium

Institute of Engineering in Medicine (IEM)
The Center for Algorithmic and Systems Biology (CASB)
UCSD Department of Bioengineering
Illumina, Inc.

Next-generation sequencing is revolutionizing our knowledge of the human and other genomes and is increasingly being used in new and unexpected areas. This meeting is intended to help the next-generation of scientists to extend the use and application of this exciting technology. If you are new to next-generation sequencing this meeting will be an excellent introduction to the current state of the art as well as an overview of new applications that may be applicable to your research. There will also be presentations on the latest data analysis algorithms and data analysis tools for experienced researchers who are currently doing next-generation sequencing or are involved in data analysis.

The first day of the meeting will start with the latest in resequencing and de novo sequencing. In the afternoon the focus will shift to the algorithmic developments that are driving the increase in data quality and volume that has become the hallmark of this technology. The ever-critical sequence alignments algorithms and programs will also be covered. During the evening there will be an optional workshop to demonstrate the practical steps that go into designing an experiment and the data analysis pipeline required to analyze and interpret the data.

The second day of the meeting will be devoted to new applications of this technology. It seems that every month there is a crop of journal articles describing new, and sometimes surprising, applications. This session will cover digital gene expression, epigenetics, targeted resequencing, protein-DNA interactions (Chip-Seq), genotyping, SNP mapping and SNP discovery.

We hope you will be able to join us to explore this new and exciting field.

Shankar Subramaniam
Pavel Pevzner
Jacques Retief